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Glenmark plans to file an Investigational New Drug (IND) application to initiate a Phase 1 study in the second half of CY 2017.

Allergic rhinitis is a common chronic respiratory illness that affects quality of life, productivity, and other comorbid conditions, including asthma.The newer, second-generation (ie, nonsedating) antihistamines are usually preferable to avoid sedation and other adverse effects associated with the older, first-generation antihistamines.Ocular antihistamine drops (for eye symptoms), intranasal antihistamine sprays, intranasal cromolyn, intranasal anticholinergic sprays, and short courses of oral corticosteroids (reserved for severe, acute episodes only) may also provide relief.Targeted symptom control with immunotherapy and asthma evaluation should be considered when appropriate.2Other interventions that do not have documented effectiveness in the prevention of allergic rhinitis include breastfeeding, delayed exposure to solid foods in infancy or to pets in childhood, and the use of air filtration systems.Antihistamines are medicines often used to relieve symptoms of allergies, such as hay fever, hives, conjunctivitis and reactions to insect bites or stings.GBR 1342, a CD38x CD3 bispecific antibody based on Glenmark’s proprietary BEAT® platform.

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